Applications A
wide variety of chemical based processes are in use today in the industry and
a majority of them have drawback from economic and environmental standpoints.
The industry is abound with:
Non-specific
reactions that result in poor product yields.
High
temperatures and/or high pressures needed to drive reactions that result in high
energy costs and require large volumes of cooling water downstream
Harsh
and hazardous processes involving high temperatures, pressures, acidity or alkalinity
needing high capital investment and specially designed equipment and control systems
Unwanted
by-products that prove to be difficult or costly to dispose of
High
chemical and energy consumption as well as harmful by-products that have a negative
impact on the environment
Similarly,
drugs used today in healthcare have inherent side-effects. Conventional therapies
and drugs such as Antibiotics, Non-steroidal anti-inflammatory drugs (NSAIDs:
COX-1 and COX-2 inhibitors), CNS Acting Drugs, Hormones, etc which are the most
widely prescribed in the treatment of various ailments have several known and
documented side effects. All
of these drawbacks can be virtually eliminated by using enzymes. In
Industries enzyme reactions are carried out under mild conditions, they are highly
specific, involve very fast reaction rates, and are carried out by numerous enzymes
with different roles. In addition, as only small amounts of enzymes are required
to carry out chemical reactions even on an industrial scale, both solid and liquid
enzyme preparations take up very little storage space. Mild operating conditions
enable uncomplicated and widely available equipment to be used, and enzyme reactions
are easily controlled and can be stopped when the desired degree of substrate
conversion has been achieved. Enzymes also reduce the impact of manufacturing
on the environment by reducing the consumption of chemicals and energy, and the
subsequent generation of waste. In
healthcare, enzymes play the role of biological catalysts. They are ubiquitously
found in nature and are responsible for the myriad reactions taking place in living
organisms. Not only do they orchestrate the break down of complex molecules into
simple molecules useful to the living organism, but they also regulate and control
each and every process that keeps the organism functioning harmoniously. Enzyme
action is highly specific and is well known and well characterized. Each enzyme
has its own specific role and activity and has typical biochemical properties.
Healthy tissues and cells have natural mechanisms protecting them from enzyme
action. The organism consists of checks and balances in the form of inhibitors,
which enable enzymes to function properly without deactivation. Industrial
and Healthcare enzymes primarily originate from biological systems; they contribute
to sustainable development through being isolated from microorganisms which are
fermented using primarily renewable resources. Developments
in genetic and protein engineering have led to improvements in the stability,
economy, specificity and overall application potential of industrial enzymes.
When all the benefits of using enzymes are taken into consideration, it's not
surprising that the number of commercial applications for enzymes is increasing
every year.
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